Thursday, February 23rd, 2012 • by Dr. Gregory Brown
The hormone melatonin comes from the pineal gland, which is located in the brain. Melatonin is produced by the amino acid tryptophan and helps to regulate the body’s sleep and wake cycles, known as circadian rhythms.
Melatonin in small amounts can be found in fruits, vegetables, grains and meats. It is also sold as as a dietary supplement at health food stores or over the internet on vitamin websites.
The natural cycle of sleeping and waking is controlled by your body’s own internal clock. Your body clock decides how much melatonin your body should manufacture, based on the amount of light you are exposed to during the day.
Typically, the level of melatonin in your body begins to rise after 9 p.m. or so, and then remains at a high level during most of the night. As dawn approaches, melatonin levels start to decline and the body prepares to wake itself up.
The amount of melatonin your body produces is affected by your exposure to light. That’s why some people can have trouble sleeping in the winter when the days are shorter, and may also suffer from seasonal affective disorder (SAD).
Melatonin levels in the body decline gradually as we get older. There are some elderly persons whose bodies may produce hardly any melatonin at all, leading to sleeping disorders like insomnia.
Melatonin supplements can help treat chronic sleeplessness in senior citizens. Melatonin can also help people who have trouble falling asleep due to jet lag or working the night shift.
Research is being done to see if melatonin tablets can slow or even stop the spread of cancer. Melatonin has shown strong antioxidant effects, and preliminary research suggests that it may help strengthen the immune system. Taking melatonin may allow people to age more slowly.
Several studies have shown a link between melatonin levels and breast cancer risk. For example, women diagnosed with breast cancer tend to have lower levels of melatonin than women without the disease.
Melatonin side effects may include headache, stomach trouble, lowered body temperature and general sluggishness upon awakening. People taking melatonin may also experience drowsiness and must be very careful when operating machinery or driving a car.
Melatonin supplements are normally safe in low dosages for short or long periods of time. But it is important to consult with a doctor before beginning melatonin sleep therapy. Children under 12 and women who are pregnant or breastfeeding should avoid taking melatonin without a doctor’s permission.
The proper dosage of melatonin fluctuates widely from individual to individual, but most adults are safe taking 1 to 2 milligrams before bedtime. Consult with a physician to find out what dosage is best for you.
Melatonin supplements are available at drug stores, health food shops and through online pharmacies. Avoid melatonin made from cow pineal glands – only take natural melatonin that is man-made and safe for human use. Melatonin comes in capsule, tablet, cream and lozenge forms.